posts: 25159

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                        "text": "Even after ",
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                        "url": "https://owid.cloud/malaria-past-prevalence",
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                                "text": "a century of progress",
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                        "text": " against malaria, the disease remains devastating for millions. The World Health Organization estimates that 216 million suffered from the disease in 2016.{ref}Figures for 2016 according to the WHO: ",
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                        "url": "http://www.who.int/malaria/en/",
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                                "text": "http://www.who.int/malaria/en/",
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                        "text": "{/ref}",
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                        "text": "Fortunately only a small fraction of malaria victims die of the disease. But those who die are the very weakest; three out of four malaria victims are children younger than 5 years old making it one of the leading causes of child mortality in the world today.{ref}The age-specific mortality figures are those published by the IHME\u2019s Global Burden of Disease [the WHO does not publish country-level data on malaria deaths by age]. The share of children younger than 5 among malaria victims fell slightly over the course of the last generation, from 79% in 1990 to 72% in 2015. Here is the data: ",
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                        "url": "https://ourworldindata.org/grapher/malaria-deaths-by-age?stackMode=relative",
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                                "text": "https://ourworldindata.org/grapher/malaria-deaths-by-age?stackMode=relative",
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                        "text": "{/ref}",
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                                "text": "The world is making progress against malaria",
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                                "text": "In the history of improving population health, the most important progress is made in the prevention of disease; for infectious diseases, this means interrupting its transmission. But humanity\u2019s most ingenious and successful way of transmission interruption \u2013 immunization through vaccines \u2013 is not yet available for malaria. However, very recent developments are encouraging; at the time of writing (2019) the WHO has ",
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                            {
                                "url": "https://www.theguardian.com/global-development/2019/apr/23/malawi-trial-child-malaria-vaccine-landmark",
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                                        "text": "rolled out",
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                                "text": " a first large-scale trial of a vaccine.{ref}Alphonse Laveran discovered already in 1880 that the Plasmodium parasite is the cause for malaria. But all earlier attempts of developing a vaccines were unsuccessful. Malaria vaccines such as SPf66 were insufficiently effective and until recently none of the scientific efforts led to a licensed vaccine. For an overview see Adrian V. S. Hill (2011) \u2013 Vaccines against malaria. In Philos Trans R Soc Lond B Biol Sci. 2011 Oct 12; 366(1579): 2806\u20132814. doi: 10.1098/rstb.2011.0091. This has possibly changed with the malaria vaccine ",
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                            {
                                "url": "https://www.malariavaccine.org/malaria-and-vaccines/first-generation-vaccine/rtss",
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                                        "children": [
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                                                "text": "RTS,S",
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                                "text": ", the world's first licensed malaria vaccine, which has been approved by European regulators in 2015. See RTS,S Clinical Trials Partnership (2015) \u2013 Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial. In The Lancet, Volume 386, ISSUE 9988, P31-45, July 04, 2015. Online ",
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                                "url": "https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)60721-8/abstract",
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                                        "text": "here",
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                                "text": ".{/ref}",
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                                "text": "But we have other weapons in our arsenal.",
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                                "text": "One line of humanity\u2019s attack on the mosquito-borne fever is to progressively reduce the area in which malaria is prevalent. A second one is to prevent the transmission of the parasite where it is still prevalent. It is a surprisingly simple technology that stopped transmission and saved the lives of millions in the last few years alone.",
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                                "text": "The years since the turn of the millennium were an extraordinarily successful era in the fight against malaria. The two maps shows the change of malaria mortality for children in the region where the disease causes the highest death toll.",
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                                "text": "From 2000 to 2015 the number of malaria deaths fell by ",
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                                "url": "https://ourworldindata.org/grapher/global-malaria-deaths-by-world-region",
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                                        "text": "almost 40%",
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                                "text": ", from 896,000 deaths per year to 562,000, according to the World Health Organization.{ref}Both the WHO and the IHME report a strong decline of malaria deaths since 2000. But throughout this period the IHME consistently estimates the number of annual deaths to be higher. For more details on the differences between these two global sources see our entry on malaria ",
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                                "url": "https://ourworldindata.org/malaria",
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                                        "text": "https://ourworldindata.org/malaria",
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                                "text": "{/ref}",
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                                "text": "A recent publication in ",
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                                        "text": "Nature",
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                                "text": "{ref}Bhatt et al. (2015) \u2013 The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015. Nature 526, 207\u2013211 (08 October 2015) doi:10.1038/nature15535. Online ",
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                                "url": "https://www.nature.com/nature/journal/v526/n7572/abs/nature15535.html",
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                                        "text": "here",
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                                "text": ".{/ref} studied what made this success possible. The focus of the study was Africa, where \u2013 as the chart shows \u2013 most of the recent reduction was achieved. The researchers found that the single most important contributor to the decline was the increased distribution of insecticide-treated bed nets. The bed nets protect those who sleep under them.",
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                                "text": "The insecticide used on the bed nets kills the mosquitoes. So a community where a sufficiently high number of people sleep under bed nets the entire community is protected, regardless of whether they themselves use the bed nets. This is similar to the positive externality effect that vaccination has on communities.",
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                                "text": "The authors of the ",
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                                        "text": "Nature ",
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                                "text": "study estimate that bed nets alone were responsible for averting 451 million cases of malaria in Africa between 2000 and 2015. The other two interventions that were important for the reduction in the disease burden of malaria were indoor residual spraying (IRS) and the treatment of malaria cases with artemisinin-based combination therapy (ACT). The study's authors estimate that the three interventions averted 663 million cases of malaria in the 15 year period. Insecticide-treated bed nets were by far the most important intervention of the three, preventing 68% of the averted cases.",
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                                "text": "We can do more",
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                                "text": "Progress never happens by itself. For millennia our ancestors were exposed to the malaria parasite without defense; the fact that this changed is the achievement of the scientific and political work of the last few generations.",
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                                "text": "Today we are in the fortunate situation that we have some decades of progress behind us: We can study what worked and use this knowledge to go further.",
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                                "text": "To continue the improvement in global health more has to be done, and more can be done. Some of the most important research in global development asks the question where donations can do the most good. It\u2019s not always the case that donations do much good. Often it is unfortunately not possible to achieve much progress by donating money because funding is not the limiting constraint or the proposed solution does not actually work. But in some areas we can achieve extraordinary progress by making funding available. A charity evaluator that is doing very rigorous work is \u2018GiveWell\u2019 and on the very top of their ",
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                                "url": "https://www.givewell.org/charities/top-charities",
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                                        "text": "recommended charities",
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                                "text": " are two organizations that are fighting malaria \u2013 the ",
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                                "children": [
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                                        "text": "Against Malaria Foundation",
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                                "text": " and the ",
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                                        "text": "Malaria Consortium",
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                                "text": ".",
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                                "text": "The diseases many children die from are preventable \u2013 we therefore know that we can continue this reduction of child mortality, if we choose to do so. What is different from the past and what makes the deaths of children so appalling today is that we now know how to prevent them.",
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                                "text": "The evidence shows that the fight against malaria is still underfunded; it will depend on this funding and work whether it is possible to continue our progress against it.{ref}The latest data for Sub-Saharan Africa (from 2013) \u2013 where more than 90% of all malaria deaths occur \u2013 shows that fewer than half of all children under five sleep under an insecticide treated bed-nets. See the chart here: ",
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                                "url": "https://ourworldindata.org/grapher/share-of-children-younger-than-5-who-sleep-under-an-insecticide-treated-bednet-to-prevent-malaria?tab=chart",
                                "children": [
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                                        "text": "https://ourworldindata.org/grapher/share-of-children-younger-than-5-who-sleep-under-an-insecticide-treated-bednet-to-prevent-malaria?tab=chart",
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                                "text": "{/ref}",
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                                "text": "It requires commitment from governments around the world, but it is also something where each of us individually can contribute. Every one of us can contribute so that we continue to reduce the number of children that die in the world.",
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                                        "text": "If you want to know more before you donate, GiveWell\u2019s information on malaria can be found ",
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                                        "url": "https://www.givewell.org/international/health/malaria",
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                                                "text": "here",
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                                        "text": "And if you want to donate right away to help the successful fight against malaria you can do so via the page of ",
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                                        "url": "https://www.givewell.org/charities/top-charities",
                                        "children": [
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                                                "text": "GiveWell\u2019s recommended charities",
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                                        "text": ".",
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        "type": "article",
        "title": "Bednets malaria",
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        "dateline": "October 3, 2019",
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    "createdAt": "2019-10-03T13:37:02.000Z",
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    "updatedAt": "2023-04-25T14:29:33.000Z",
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