variables: 414008
Data license: CC-BY
This data as json
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414008 | Total circulating vaccine-derived poliovirus cases per million | Circulating vaccine-derived poliovirus (cVDPV) cases refer to cases of paralytic polio who have been infected by a poliovirus strain that was derived from a vaccine and where there is evidence that the strain has undergone community transmission. These are defined in several steps: if a child under the age of 15 presents with acute flaccid paralysis (AFP) or someone of any age presents with paralysis that is suspected to be polio, they are considered a suspected case of paralytic polio. Two stool samples are taken (between 24–48 hours apart) from these suspected cases within 15 days of the onset of paralysis and tested for the presence of the poliovirus. This process is described by the World Health Organization here: https://web.archive.org/web/20210423203212/https://www.who.int/immunization/monitoring_surveillance/burden/vpd/surveillance_type/active/poliomyelitis_standards/en/ To identify whether those strains have been derived from a vaccine (VDPV), the genome sequence of the sample is compared to that of the strains in the oral poliovirus vaccine. If there is a divergence* between the strain isolated from a case and the strain used in the vaccine, the isolated virus is considered vaccine derived. To identify whether there has been community transmission (cVDPV), there must be genetically-linked VDPVs from: at least two individuals who are not direct (household) contacts, from one individual and one environmental sample, or from two environmental samples taken at different times or from different sites. cVDPVs are categorized according to which of the 3 strains of the OPV they are derived from (cVDPV1, cVDPV2, or cVDPV3). Data is available for all cVDPVs since 2000, and for each cVDPV individually since 2016. This definition is described by the Global Polio Eradication Initiative (GPEI) here: https://web.archive.org/web/20220306074558/https://polioeradication.org/wp-content/uploads/2016/09/Reporting-and-Classification-of-VDPVs_Aug2016_EN.pdf Source: Data from 2016–2021 comes from the Global Polio Eradication Initiative (GPEI) reports: https://polioeradication.org/polio-today/polio-now/this-week/circulating-vaccine-derived-poliovirus/ Combined data from all three strains is available from 2001–2015 and comes from the WHO extranet case count: https://extranet.who.int/polis/public/CaseCount.aspx Population by country, available from 1800 to 2021 based on Gapminder data, HYDE, and UN Population Division (2019) estimates. | 2022-04-05 15:09:16 | 2023-06-15 05:05:42 | 5573 | 21964 | { "name": "Total cVDPV cases per million", "unit": "per million", "includeInTable": true } |
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